"Twelve patients were recruited and randomized (aged 60 ± 14 years, 83% females) with group I PAH (n = 11) or chronic thromboembolic pulmonary hypertension (n = 1). There was no significant difference in maximal inspiratory pressure (78.2 ± 29.3 vs 67.3 ± 17.3 cmH2O, p = 0.45) or six-minute walk distance (495 ± 154 vs 550 ± 61 meters, p = 0.44) at baseline between the IMT (n = 6) and control (n = 6) groups. Following IMT, the training group demonstrated significantly improved maximal inspiratory muscle strength compared to controls (30.8 ± 15.4 vs 10.3 ± 8.3 cmH2O, p = 0.02). Six-minute walk distance improved in the IMT group by 25 ± 18 meters compared to the control group, which fell by 12 ± 31 meters (p = 0.03). There was no significant difference in peak oxygen uptake post-intervention between groups (1.9 ± 1.3 vs 1.5 ± 2.7 ml/kg/min, p = 0.77). There were no significant changes between groups in pulmonary function testing parameters or maximal expiratory pressure (p > 0.05)." To read more, click here.
"Twelve patients were recruited and randomized (aged 60 ± 14 years, 83% females) with group I PAH (n = 11) or chronic thromboembolic pulmonary hypertension (n = 1). There was no significant difference in maximal inspiratory pressure (78.2 ± 29.3 vs 67.3 ± 17.3 cmH2O, p = 0.45) or six-minute walk distance (495 ± 154 vs 550 ± 61 meters, p = 0.44) at baseline between the IMT (n = 6) and control (n = 6) groups. Following IMT, the training group demonstrated significantly improved maximal inspiratory muscle strength compared to controls (30.8 ± 15.4 vs 10.3 ± 8.3 cmH2O, p = 0.02). Six-minute walk distance improved in the IMT group by 25 ± 18 meters compared to the control group, which fell by 12 ± 31 meters (p = 0.03). There was no significant difference in peak oxygen uptake post-intervention between groups (1.9 ± 1.3 vs 1.5 ± 2.7 ml/kg/min, p = 0.77). There were no significant changes between groups in pulmonary function testing parameters or maximal expiratory pressure (p > 0.05)." To read more, click here.