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For patients with PAH, initial double oral combination therapy is recommended for treatment. At this time, no data are available on initial triple oral combination therapy. Therefore, researchers evaluated the efficacy and safety of initial triple oral therapy with selexipag, macitentan, and tadalafil compared with initial double oral therapy with macitentan and tadalafil in 247 newly diagnosed, treatment-naive patients with PAH.

Read the article here.

Read the research here.